Streptomycin sulfate
Streptomycin sulfate
CAS: 3810-74-0
Molecular Formula: C21H41N7O16S
Streptomycin sulfate - Names and Identifiers
| Name | Streptomycin sulfate |
| Synonyms | Verstrep Strep-sol Streptomyc Streptomycin sulfate Streptomycin sulphate STREPTOMYCIN SESQUISULFATE N'',N'''''-[(1R,2R,3S,4R,5R,6S)-4-({(2xi)-5-deoxy-2-O-[2-deoxy-2-(methylamino)-alpha-L-glucopyranosyl]-3-C-formyl-alpha-L-threo-pentofuranosyl}oxy)-2,5,6-trihydroxycyclohexane-1,3-diyl]diguanidine sulfate (salt) 2-[(1S,2R,3S,4S,5R,6S)-5-(diaminomethylideneamino)-2-[(2R,3S,4S,5R)-3-[(2R,3R,4R,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-methylamino-oxan-2-yl]oxy-4-formyl-4-hydroxy-5-methyl-oxolan-2-yl]oxy-3,4,6-trihydroxy-cyclohexyl]guanidine |
| CAS | 3810-74-0 |
| EINECS | 223-286-0 |
| InChI | InChI=1/2C21H39N7O12.3H2O4S/c2*1-5-21(36,4-30)16(40-17-9(26-2)13(34)10(31)6(3-29)38-17)18(37-5)39-15-8(28-20(24)25)11(32)7(27-19(22)23)12(33)14(15)35;3*1-5(2,3)4/h2*4-18,26,29,31-36H,3H2,1-2H3,(H4,22,23,27)(H4,24,25,28);3*(H2,1,2,3,4)/t2*5-,6-,7-,8+,9-,10-,11-,12+,13-,14-,15-,16-,17-,18-,21+;;;/m00.../s1 |
| InChIKey | QTENRWWVYAAPBI-YZTFXSNBSA-N |
Streptomycin sulfate - Physico-chemical Properties
| Molecular Formula | C21H41N7O16S |
| Molar Mass | 679.65 |
| Density | 1.2302 (rough estimate) |
| Melting Point | >185°C (dec.) |
| Boling Point | 948.2°C at 760 mmHg |
| Specific Rotation(α) | -79～-88°(20℃/D)(c=1,H2O)(calculated on the dried basis) |
| Flash Point | 527.3°C |
| Water Solubility | >=0.01 g/100 mL at 18 ºC |
| Solubility | Soluble in water. |
| Vapor Presure | 0mmHg at 25°C |
| Appearance | powder |
| Color | white to off-white |
| Merck | 14,8826 |
| BRN | 3894995 |
| PH | pH (100g/l, 25℃) : 4.5～7.0 |
| Storage Condition | 2-8°C |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| Refractive Index | -85 ° (C=1, H2O) |
| MDL | MFCD00037023 |
| Physical and Chemical Properties | Water solubility> = 0.01g/100 mL at 18°C |
| Use | For tuberculosis, brucella and non-hemolytic streptococcal infective endocarditis, plague and tularemia, influenza bacilli and gram-negative bacilli infection treatment |
Streptomycin sulfate - Risk and Safety
| Risk Codes | R22 - Harmful if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin. R63 - Possible risk of harm to the unborn child R42/43 - May cause sensitization by inhalation and skin contact. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S36/37 - Wear suitable protective clothing and gloves. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S22 - Do not breathe dust. S60 - This material and its container must be disposed of as hazardous waste. |
| WGK Germany | 3 |
| RTECS | WK4990000 |
| FLUKA BRAND F CODES | 3 |
| TSCA | Yes |
| HS Code | 29412000 |
Streptomycin sulfate - Upstream Downstream Industry
| Raw Materials | Potassium Phosphate Monobasic Cobaltous chloride |
Streptomycin sulfate - Reference
| Reference Show more | 1. Wu Yu, Rui bin, Ye Feng, et al. Effect of propofol down-regulating miR-93-5p expression on proliferation and invasion of breast cancer MDA-MB-231 cells [J]. Chinese pharmacist 2020 v.23(06):48-53. 2. Lei Nan, Feng, Liu, Tian, Huang, he, Yong, Li, Qiumei, Hong, Mei. Effect of tamoxifen on the expression of mTOR and survivin in human hepatoma HepG2 cells [J]. Cancer pharmacy 2015 5(03): -198. 3. Deng Wen, Yu Xueli, Peng Youzhi, etc. Effect of cooling rate on sperm quality during semen balance in sheep [J]. Journal of Animal Science and Veterinary Medicine, 2010, 37(004):109-112. 4. Mao with the year, Hu Jiahuan, Liu Yixiu. Inhibitory effect of Artemisia argyi extract on Staphylococcus aureus [J]. Modern food science and technology, 2018, 34(11):89-94. 5. Gao Ming-kun, Zhang Zhi, Qian Fang. Toxicity and functional test of mixed bacterial preparation (BMX) and its effect on fattening pigs [J]. Feed Research, 2018, No.485(04):66-71. 6. Cindao machine, Mai Jialin, Zhou Yuyuan, et al. Drug resistance and transmission characteristics of blaCTX-M gene in E. Coli isolated from Goose farms in Guangdong province [J]. Chinese Journal of Animal and Veterinary Medicine, 2020, 047(005):1571-1582. 7. Zhang Jipei, Wei Qinglan, Tan Hualong, etc. Study on drug resistance and aminoglycoside resistance genes of Escherichia coli isolated from waterfowl in Guangdong province [J]. Progress in animal medicine, 2016, 37(005):42-46. 8. Liu Minfang, Cao mengrui, Li Rongxu, etc. Isolation, identification and drug sensitivity analysis of salmonella from waterfowl in some areas of Guangdong province [J]. Heilongjiang Journal of Animal Science and Veterinary Medicine, 2018(10). 9. Wei Qinglan, Zhang Jipei, Ren Tao, et al. Drug Sensitivity Analysis of Escherichia coli from waterfowl in Guangdong province [J]. Heilongjiang Journal of Animal Husbandry and Veterinary Medicine, 2015, 000(012):180-181. 10. Huang Junhong. Study on the transfer conditions of oqxAB gene mediated by plasmid in Escherichia coli and the phenotype and genotype of the zygote [D]. Huazhong Agricultural University, 2020. 11. Zhang Liu-ming, Ma Jin-Liang, Feng Yunkui, Qin Chang-Jiang, Hu Huiru, tagq Sohail, Wang Yanhu, Li Yongjun. Effect of glycerol on the preservation of Hu sheep semen at room temperature [J]. Journal of Yangzhou University (Agriculture and Life Science Edition),2020,41(05):69-74. 12. [IF = 4.36] Qingsong Qu et al."Effects of fermented ginseng on the gut microbiota and immunity of rats with antibiotic-associated diarrhea."J Ethnopharmacol. 2021 Mar;267:113594 13. [IF=2.896] Xiaoyan He et al."A label-free electrochemical DNA biosensor for kanamycin detection based on diblock DNA with poly-cytosine as a high affinity anchor on graphene oxide."Anal Methods-Uk. 2020 Jul;12(27):3462-3469 14. [IF=10.588] Aiyun Guo et al.Prochloraz alone or in combination with nano-CuO promotes the conjugative transfer of antibiotic resistance genes between Escherichia coli in pure water.J Hazard Mater. 2022 Feb;424:127761 |
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Raw Materials for Streptomycin sulfate